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What is Regenerative Medicine?

April 20, 2017


Regenerative medicine is a branch of medical translational research which Regenerative Medicinedeals with molecular biology and tissue engineering. It is the science of replacing or regenerating human cells, tissues and organs for restoration of normal physiological functions. It stimulates body’s own repair mechanism for natural healing of body tissues. It also involves artificially growing of tissues and organs in laboratory. Stem Cell therapy is an important branch of regenerative medicine.

History

In the year 1992, the term "regenerative medicine" was coined by Leland Kaiser. He explained in the article how regenerative medicine will change the course of chronic diseases and holds the key to future and will impact hospitals. In June 2008, the first tissue engineered trachea transplantation occurred at the Hospital Clínic de Barcelona. In 2009, with the aim of application of regenerative medicine to reverse the aging process, the SENS Foundation was launched. In 2012, the team of Professor Paolo Macchiarini conducted a better version of the 2008 implant by transplanting a trachea made of patient’s own cells. In September 2014, in Institute of Biomedical Research and Innovation, Japan, a sheet of retinal pigment epithelium cells, differentiated from iPS cells was transplanted into the eyes of an aged woman with macular degeneration.

Applications

 Stem cell therapy- bone marrow transplant is the most commonly used stem cell therapy for treatment of diseases like leukemia, lymphoma. Lot of research is underway to investigate the effect of stem cells Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, amyotrophic lateral sclerosis, stroke, traumatic brain injury, myocardial infarction, tooth regeneration, cochlear hair cell growth, treatment of corneal diseases, restoration of vision, diabetes, wound healing, infertility, azoospermia, mesenchymal cell transplantation, veterinary medicine

Extracellular matrix materials are products of regenerative medicine and are being commercially used for reconstructive surgeries, heart surgeries, orthopedic surgeries treatment of chronic wounds etc.

Disclaimer: The information given in this write-up is purely for educating the reader. It is not meant to be a substitute for any advice from a medical expert.